|The BID bid (Catalog #MBS151406) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bid Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Bid can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
Bid antibody can be used for detection of Bid by Western blot at 0.5 to 2 mug/mL. Researchers should empirically determine the suitability of the BID bid for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BID bid product has the following accession number(s) (GI #54673639) (NCBI Accession #AAH36364) (Uniprot Accession #P55957). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bid Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Bid in A549 cell lysates with Bid antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)
Bid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.
Immunogen: Bid antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bid.
Buffer: Bid Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BID are readily searchable from our website. Different antibodies against the same target such as BID may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Skin, Stomach, Vascular tissues are correlated with this protein.