|The BLK blk (Catalog #MBS2528416) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BLK Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s BLK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the BLK blk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BLK blk product has the following accession number(s) (GI #116284012) (NCBI Accession #AAH18703.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BLK Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of A172 cell using BLK Polyclonal Antibody at dilution of 1:250)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer using BLK Polyclonal Antibody at dilution of 1:20)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastric cancer using BLK Polyclonal Antibody at dilution of 1:20)
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors.
Immunogen: Recombinant protein of human BLK
Calculated Molecular Weight: 58kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BLK are readily searchable from our website. Different antibodies against the same target such as BLK may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. BLK also interacts with the following gene(s): BLNK, CBL, CD79A, CD79B, CSK, EGFR, PLCG2, SYK. Blood, Bone Marrow, Connective Tissue, Intestine, Lung, Lymph, Lymph Node, Mammary Gland, Spleen, Thymus tissues are correlated with this protein. Arthritis, Rheumatoid, Brain Diseases, Breast Neoplasms, Immune System Diseases, Inflammation, Lung Diseases, Lupus Erythematosus, Systemic, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to BLK Polyclonal Antibody.