anti-BMP7 antibody product blog
Tags: Antibody; BMP7; Polyclonal Antibody; anti-BMP7 antibody;
The BMP7 bmp7 (Catalog #MBS6010462) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BMP7, CT (BMP7, OP1, Bone morphogenetic protein 7, Osteogenic protein 1, INN=Eptotermin alfa) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s BMP7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Optimal dilution to be determined by the researcher. Researchers should empirically determine the suitability of the BMP7 bmp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BMP7 bmp7 product has the following accession number(s) (GI #4502427) (NCBI Accession #NP_001710.1) (Uniprot Accession #P18075). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BMP7, CT (BMP7, OP1, Bone morphogenetic protein 7, Osteogenic protein 1, INN=Eptotermin alfa) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis in 293 cell lysates (2ug/lane) using MBS6010462, either nontransfected (Lane 1) or transiently transfected (Lane 2) with the BMP7 gene.)
Western Blot (WB) (Western Blot analysis in mouse heart tissue lysates (35ug/lane) using MBS6010462. This demonstrates that MBS6010462 detected the BMP7 protein (arrow).)
Immunohistochemistry (IHC) (Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue using MBS6010462 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS6010462 for immunohistochemistry.)
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq].
Immunogen: BMP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of human BMP7. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BMP7 are readily searchable from our website. Different antibodies against the same target such as BMP7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.