|The BMPR2 bmpr2 (Catalog #MBS355060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Bone morphogenetic protein receptor type II, BMPR2 antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Bone morphogenetic protein receptor type II, BMPR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC).
WB (1:1000-2000); ICC (1:100-500); Flow Cytometryt (1:10-100). Researchers should empirically determine the suitability of the BMPR2 bmpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BMPR2 bmpr2 product has the following accession number(s) (GI #15451916) (NCBI Accession #NP_001195.2) (Uniprot Accession #Q13873). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Bone morphogenetic protein receptor type II, BMPR2 antibody with the following immunoassay(s):
Western Blot (WB)
Bone morphogenetic protein receptor type II, BMPR2 is a serine/threonine receptor kinase. It binds bone morphogenetic proteins, members of the TGF beta superfamily of ligands. BMPs are involved in a host of cellular functions including osteogenesis, cell growth and cell differentiation. Unlike the TGFbetatype II receptor, which has a high affinity for TGF-beta1, BMPR2 does not have a high affinity for BMP-2, BMP-7 and BMP-4, unless it is co-expressed with a type I BMP receptor.1 The low affinity for ligands suggests that BMPR2 may differ in the from other type II TGF beta receptors in that the ligand may bind the type I receptor first.2.
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of BMPR2. Storage Buffer: In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide
Storage Buffer: In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BMPR2 are readily searchable from our website. Different antibodies against the same target such as BMPR2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Hypertension, Hypertension, Pulmonary, Hypertrophy, Inflammation, Neoplasms, Nervous System Diseases, Pulmonary arterial hypertension are some of the diseases may be linked to Anti-Bone morphogenetic protein receptor type II, BMPR2 antibody.