anti-C-JUN antibody product blog
Tags: Antibody; anti-c-Jun antibody; c-Jun; Polyclonal Antibody;
The C-JUN jun (Catalog #MBS625068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The c-Jun, phosphorylated (Ser73) (Transcription Factor AP-1, Activator Protein 1, AP1, Proto-oncogene c-Jun, V-jun Avian Sarcoma Virus 17 Oncogene Homolog, p39, JUN) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s c-Jun can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:500-1:1,000
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the C-JUN jun for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The C-JUN jun product has the following accession number(s) (GI #1911701) (Uniprot Accession #P56432). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Immunogen: Synthetic phosphopeptide corresponding to human c-Jun around the phosphorylation site of serine 73 (L-A-SP-P-E). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C-JUN are readily searchable from our website. Different antibodies against the same target such as C-JUN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Heart, Intestine, Joint, Lung, Muscle, Skin, Stomach tissues are correlated with this protein.