|The C-myc c-myc (Catalog #MBS534611) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The C-myc antibody reacts with To be determined by end-user and may cross-react with other species as described in the data sheet. MyBioSource\'s C-myc can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB).
WB: colorimetric: 1:1,000-1:10,000
chemiluminescent: 1:1,000-1:30,000. Researchers should empirically determine the suitability of the C-myc c-myc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The C-myc c-myc product has the following accession number(s) (GI #396512) (NCBI Accession #CAA46984.1) (Uniprot Accession #Q6LBK7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Chicken polyclonal C-myc antibody.
Biological Significance: Myc gene encodes a transcription factor that is believed to regulate expression of 15% of all genes through binding of Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). This means that in addition to its role as a classical transcription factor, Myc also functions to regulate global chromatin structure. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: C-myc antibody was raised in chicken using residues 410-419 (EQKLISEEDL) of human myc conjugated to KLH as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C-myc are readily searchable from our website. Different antibodies against the same target such as C-myc may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. C-myc also interacts with the following gene(s): CDKN2A, EP300, FBXW7, GSK3B, KAT5, MAX, PFDN5, SKP2, SUPT3H, ZBTB17. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein.