|The C3HC4 n/a (Catalog #MBS839420) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The C3HC4 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s C3HC4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1 ug/ml. Researchers should empirically determine the suitability of the C3HC4 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the C3HC4 antibody with the following immunoassay(s):
Western Blot (WB) (C3HC4 antibody (MBS839420) used at 1 ug/ml to detect target protein.)
Rabbit polyclonal C3HC4 antibody.
Biological Significance: MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6. Immunogen: C3HC4 antibody was raised using a synthetic peptide corresponding to a region with amino acids LFITPLAAISGWLCLRGAQDHLRLHSQLEAVGLIALTIALFTIYVLWTLV. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C3HC4 are readily searchable from our website. Different antibodies against the same target such as C3HC4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.