anti-CACNA1H antibody product blog
Tags: Antibody; Polyclonal Antibody; Cacna1h; anti-CACNA1H antibody;
The CACNA1H cacna1h (Catalog #MBS153412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CACNA1H Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CACNA1H can be used in a range of immunoassay formats including, but not limited to, ELISA, IF, IHC-P, WB.CACNA1H antibody can be used for detection of CACNA1H by Western blot at 1 - 2 mug/ml. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CACNA1H cacna1h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CACNA1H cacna1h product has the following accession number(s) (GI #53832009) (NCBI Accession #NP_066921) (Uniprot Accession #O95180). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CACNA1H Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of CACNA1H in 293 cell lysate with CACNA1H antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC) (Immunohistochemistry of CACNA1H in mouse brain tissue with CACNA1H antibody at 5 μg/ml.)
Immunofluorescence (IF) (Immunofluorescence of CACNA1H in mouse brain tissue with CACNA1H antibody at 20 μg/ml.)
The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2). CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3). CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4).
Conjugate: Unconjugated
Immunogen: CACNA1H antibody was raised against a 16 amino acid peptide near the center of human CACNA1H.
Buffer: CACNA1H antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CACNA1H are readily searchable from our website. Different antibodies against the same target such as CACNA1H may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.