anti-CACNA1S antibody product blog
Tags: Antibody; Polyclonal Antibody; CACNA1S; anti-CACNA1S antibody;
The CACNA1S cacna1s (Catalog #MBS837444) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CACNA1S can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB).IHC-P: 1:100-1:500
WB: 1:500-1:3000. Researchers should empirically determine the suitability of the CACNA1S cacna1s for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CACNA1S cacna1s product has the following accession number(s) (GI #134152372) (NCBI Accession #AAI33672.1) (Uniprot Accession #Q13698). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CACNA1S antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded Cal27 xenograft using CACNA1S antibody at a dilution of 1:100)
Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: 293T) using a 5 % SDS PAGE gel and CACNA1S antibody at a dilution of 1:1000)
Affinity purified Rabbit polyclonal CACNA1S antibody.
Biological Significance: This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. Cross-Reactivity: Human
Immunogen: CACNA1S antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 544 and 885 of CACNA1S. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CACNA1S are readily searchable from our website. Different antibodies against the same target such as CACNA1S may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arrhythmias, Cardiac, Edema, Glucose Intolerance, HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1, Hyperplasia, Hypertrophy, Hypokalemic Periodic Paralysis, Malignant hyperthermia susceptibility type 5, Respiratory Insufficiency, Weight Loss are some of the diseases may be linked to CACNA1S antibody. CACNA1S also interacts with the following gene(s): CACNA1H, CACNA2D1, CACNB1, RYR1. Liver, Muscle, Thyroid tissues are correlated with this protein. The following patways have been known to be associated with this gene.