anti-CALR antibody product blog
Tags: Antibody; Polyclonal Antibody; Calreticulin; anti-CALR antibody; CALR;
The CALR calr (Catalog #MBS615434) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Calreticulin (CALR, SSA, Sicca Syndrome Antigen A, Ro, Autoantigen Ro) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Calreticulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot. Researchers should empirically determine the suitability of the CALR calr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CALR calr product has the following accession number(s) (GI #4757900) (NCBI Accession #NP_004334.1) (Uniprot Accession #P27797). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to the endoplasmic reticulum (ER). It is also a molecular chaperone and is involved in protein folding events in the ER. Calreticulin has also been shown to interact with the cytoskeleton and to be involved in the regulation of gene expression. Calreticulin may play a role in cellular proliferation including its apparent activity in the proliferation of certain viruses within mammalian host cells. Recently it has been shown that calreticulin is induced in response to various types of cell stress including amino acid deprivation.
Immunogen: A full-length protein to mouse calreticulin.
Cellular Localization: Calreticulin staining is localized to the ER in most cell types and under most conditions. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CALR are readily searchable from our website. Different antibodies against the same target such as CALR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. CALR also interacts with the following gene(s): NKX2-1, PDIA3. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Leukemia, Leukemia, Myeloid, Lung Diseases, Lung Neoplasms, Mental Disorders, Neoplasms, Schizophrenia are some of the diseases may be linked to Calreticulin (CALR, SSA, Sicca Syndrome Antigen A, Ro, Autoantigen Ro). Blood, Brain, Embryonic Tissue, Eye, Ganglia, Intestine, Kidney, Liver, Nerve, Vascular tissues are correlated with this protein.