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anti-CAPRIN2 antibody product blog

Posted on 2018-05-16 09:27:20 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; Caprin2; anti-CAPRIN2 antibody;
The CAPRIN2 caprin2 (Catalog #MBS2516464) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAPRIN2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CAPRIN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF).
WB 1:200-1:1000, IF 1:20-1:200. Researchers should empirically determine the suitability of the CAPRIN2 caprin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CAPRIN2 caprin2 product has the following accession number(s) (GI #332205983) (NCBI Accession #NP_001193785.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CAPRIN2 Antibody with the following immunoassay(s):
Western Blot (SH-SY5Y cells were subjected to SDS-PAGE followed by western blot with CAPRIN2 Polyclonal Antibody at dilution of 1:300)
Western Blot CAPRIN2.

Immunofluorescent (Immunofluorescent analysis of HepG2 cells using CAPRIN2 Polyclonal Antibody at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescent CAPRIN2.

Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (PubMed:18762581). Faciliates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling (PubMed:27821587). May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation (PubMed:14593112). May be involved in apoptosis (PubMed:14593112).

Immunogen: Fusion protein of CAPRIN2. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH7.3.
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107473 / sc-107474
Calculated MW: 1127aa,126 kDa
Observed MW: 150 kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CAPRIN2 are readily searchable from our website. Different antibodies against the same target such as CAPRIN2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Eye, Kidney, Liver, Muscle, Skin, Spleen tissues are correlated with this protein. Cell Transformation, Neoplastic, Liver Diseases, Liver Neoplasms, Necrosis are some of the diseases may be linked to CAPRIN2 Antibody.
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