anti-CASP2 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-CASP2 antibody; CASP2;
The CASP2 casp2 (Catalog #MBS9414946) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CASP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).ELISA: 1:1000-1:10000
Western blotting: 1:1000-1:2000
Immunohistochemistry: 1:100-1:300. Researchers should empirically determine the suitability of the CASP2 casp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CASP2 casp2 product has the following accession number(s) (GI #37589082) (NCBI Accession #BC002427). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CASP2 Antibody with the following immunoassay(s):
Testing Data (Gel: 10%SDS-PAGELane1: Human fetal kidney tissue lysateLane2: Human fetal lung tissue lysateLysates: 30ug per lanePrimary antibody: 1/950 dilutionSecondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilutionExposure time: 2 minutes)
Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human urinary bladder tissue using 31011(CASP2 Antibody) at dilution 1/100, on the right is treated with the fusion protein.)
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer\'s disease, Huntington\'s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Type: Recombinant protein
Immunogen Description: Fusion protein corresponding to N terminal 201 amino acids of Human Caspase-2. Target Name: CASP2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CASP2 are readily searchable from our website. Different antibodies against the same target such as CASP2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Embryonic Tissue, Liver, Lung, Nerve, Prostate, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Disease Models, Animal, Inflammation, Lung Diseases, Necrosis, Nervous System Diseases, Ovarian Neoplasms are some of the diseases may be linked to CASP2 Antibody.