anti-Casp4 antibody product blog
Tags: Antibody; Caspase 4; Polyclonal Antibody; anti-CASP4 antibody; CASP4;
The Casp4 n/a (Catalog #MBS415984) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Caspase 4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Caspase 4 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB).Recommended dilutions:
Peptide ELISA: 1:10,000
WB: 1:100 - 1:500
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the Casp4 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Casp4 n/a product has the following accession number(s) (GI #76253906) (NCBI Accession #NP_446188.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Caspase 4 Antibody with the following immunoassay(s):
Western Blot (WB)
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Storage Buffer: PBS, pH 7.4 with 0.02% Sodium Azide. Immunogen: Synthetic peptide conjugated to KLH. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Casp4 are readily searchable from our website. Different antibodies against the same target such as Casp4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.