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anti-CAV3 antibody product blog

Posted on 2015-12-31 15:06:22 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-CAV3 antibody; CAV3;
The CAV3 cav3 (Catalog #MBS2522734) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAV3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CAV3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500-1:2000
IHC: 1:25-1:100. Researchers should empirically determine the suitability of the CAV3 cav3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CAV3 cav3 product has the following accession number(s) (GI #4502589) (NCBI Accession #NP_001225.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CAV3 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Human fetal muscle tissue using CAV3 Polyclonal Antibody at dilution of 1:500)
Western Blot (WB) CAV3.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastic cancer using CAV3 Polyclonal Antibody at dilution of 1:30)
Immunohistochemistry (IHC) CAV3.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lymphoma using CAV3 Polyclonal Antibody at dilution of 1:30)
Immunohistochemistry (IHC) CAV3.

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Immunogen: Synthetic peptide of human CAV3
Calculated Molecular Weight: 17kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CAV3 are readily searchable from our website. Different antibodies against the same target such as CAV3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arrhythmias, Cardiac, Cardiomegaly, Heart Defects, Congenital, Heart Diseases, Hypertension, Hypertrophy, Inflammation, Muscular Dystrophies, Limb-Girdle, Pain, Ventricular Remodeling are some of the diseases may be linked to CAV3 Polyclonal Antibody.
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