|The CBLN1 cbln1 (Catalog #MBS615293) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cerebellin Precursor, CT (Cbln1, Precerebellin) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Cerebellin Precursor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).
Suitable for use in Western Blot and Immunocytochemistry.
Dilution: Western Blot: 2-4ug/ml
Immunocytochemistry: 10ug/ml. Researchers should empirically determine the suitability of the CBLN1 cbln1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CBLN1 cbln1 product has the following accession number(s) (GI #4757922) (NCBI Accession #NP_004343.1) (Uniprot Accession #P23435). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q (1). Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway (2); and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release (3). The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus (4). Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that.
Immunogen: Synthetic peptide corresponding to 16aa near the carboxy- terminus of human precerebellin (Genbank accession No. P23435). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CBLN1 are readily searchable from our website. Different antibodies against the same target such as CBLN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CBLN1 also interacts with the following gene(s): CBLN3. Brain, Embryonic Tissue, Ganglia, Ovary, Testis, Uncharacterized Tissue tissues are correlated with this protein. Neurodegenerative Diseases are some of the diseases may be linked to Cerebellin Precursor, CT (Cbln1, Precerebellin).