anti-ccbe1 antibody product blog
Tags: Antibody; Polyclonal Antibody; ccbe1; anti-CCBE1 antibody;
The ccbe1 ccbe1 (Catalog #MBS691286) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Anti-Human ccbe1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ccbe1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF).IF/IHC: Use 2-10 ug/ml Western Blot: Use 2-5 mg/ml. Researchers should empirically determine the suitability of the ccbe1 ccbe1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ccbe1 ccbe1 product has the following accession number(s) (GI #39930511) (NCBI Accession #NP_597716.1) (Uniprot Accession #Q6UXH8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Anti-Human ccbe1 with the following immunoassay(s):
Testing Data
The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish. ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.
Immunogen: Recombinant human ccbe1 (Sf9)
Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant human ccbe1 (Tyr35-Pro406) derived from Sf9 insect cells. Buffer: PBS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ccbe1 are readily searchable from our website. Different antibodies against the same target such as ccbe1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.