anti-CCL22 antibody product blog
Tags: Antibody; Polyclonal Antibody; CCL22; anti-CCL22 antibody;
The CCL22 ccl22 (Catalog #MBS126619) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CCL22 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).1:50-1:100. Researchers should empirically determine the suitability of the CCL22 ccl22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CCL22 ccl22 product has the following accession number(s) (GI #311033357) (NCBI Accession #O00626.2) (Uniprot Accession #O00626). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CCL22 with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat kidney using CCL22 antibody (MBS126619) at dilution of 1:100 (40x lens).)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human colon using CCL22 antibody (MBS126619) at dilution of 1:100 (40x lens).)
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CCL22 (NP_002981.2)
Species Reactivity/Cross Reactivity: Human, Rat. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCL22 are readily searchable from our website. Different antibodies against the same target such as CCL22 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CCL22 also interacts with the following gene(s): CCL17, CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CCR8, CXCR3. The following patways have been known to be associated with this gene. Carcinoma, Dermatitis, Atopic, Hypersensitivity, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Respiratory Hypersensitivity, Respiratory Tract Diseases, Skin Diseases are some of the diseases may be linked to CCL22.