|The CCNE2 ccne2 (Catalog #MBS355110) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Cyclin E2 antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Cyclin E2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC).
WB (1:5000). Researchers should empirically determine the suitability of the CCNE2 ccne2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CCNE2 ccne2 product has the following accession number(s) (GI #4008085) (NCBI Accession #AAD08816.1) (Uniprot Accession #O96020). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Cyclin E2 antibody with the following immunoassay(s):
Western Blot (WB)
Cyclin E2 is a member of the cyclin family, It is a predicted 404-amino acid protein which contains a cyclin box motif and it is 47% identical to cyclin E1.  It is expressed in several normal human tissues, with the highest levels in testis, thymus, and brain. Gudas et al. (1999) found that, like cyclin E1, the human cyclin E2 gene complemented a G1 cyclin defect in S. cerevisiae. Cyclin E2 expressed in mammalian cells associated with CDK2 in a functional kinase complex that was inhibited by both KIP1 and CIP1. .
Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of Cyclin E2. Storage Buffer: In TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide
Storage Buffer: In TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCNE2 are readily searchable from our website. Different antibodies against the same target such as CCNE2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Drug-Induced, Breast Neoplasms, Carcinoma, Cell Transformation, Neoplastic, Liver Diseases, Lung Diseases, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Skin Neoplasms are some of the diseases may be linked to Anti-Cyclin E2 antibody. CCNE2 also interacts with the following gene(s): CDC25A, CDK1, CDK2, CDKN1A, CDKN1B, CDKN1C, E2F1. The following patways have been known to be associated with this gene.