anti-CCR3 antibody product blog
Tags: Antibody; Polyclonal Antibody; CCR3; anti-CCR3 antibody;
The CCR3 ccr3 (Catalog #MBS627260) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCR3, ID (CD193, CC Chemokine Receptor Type 3, CC CKR 3, CC CKR3, B Chemokine Receptor, CMKBR3, Eosinophil CC Chemokine Receptor 3, Eosinophil Eotaxin Receptor, MGC102841) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CCR3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the CCR3 ccr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CCR3 ccr3 product has the following accession number(s) (GI #257743046) (NCBI Accession #NP_847898.1) (Uniprot Accession #P51677). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CCR3, ID (CD193, CC Chemokine Receptor Type 3, CC CKR 3, CC CKR3, B Chemokine Receptor, CMKBR3, Eosinophil CC Chemokine Receptor 3, Eosinophil Eotaxin Receptor, MGC102841) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of CCR3 Antibody (Center) in Jurkat cell line lysates (35ug/lane). CCR3 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS) (CCR3 Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Immunogen: Synthetic peptide selected from the Center region of human CCR3 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCR3 are readily searchable from our website. Different antibodies against the same target such as CCR3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.