anti-CD14 antibody product blog
Tags: Antibody; Polyclonal Antibody; CD14; anti-CD14 antibody;
The CD14 cd14 (Catalog #MBS859660) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CD14 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:1,000. Researchers should empirically determine the suitability of the CD14 cd14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD14 cd14 product has the following accession number(s) (GI #4557417) (NCBI Accession #NP_000582.1) (Uniprot Accession #P08571). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD14 Antibody with the following immunoassay(s):
Testing Data (Western blot analysis on K562 cell lysates using anti-CD14 rabbit polyclonal antibody.)
CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.
Cellular Localization: Cell Membrane. Positive Control: K562 cell lysate. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD14 are readily searchable from our website. Different antibodies against the same target such as CD14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD14 also interacts with the following gene(s): ITGB2, LBP, LY86, LY96, TICAM2, TLR1, TLR2, TLR4. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. Asthma, Atherosclerosis, Cardiovascular Diseases, Drug Toxicity, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to CD14 Antibody.