anti-CD167 antibody product blog
Tags: Antibody; Polyclonal Antibody; CD167; anti-CD167 antibody;
The CD167 ddr1 (Catalog #MBS221418) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CD167 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Paraffin*.Immunohistology - Paraffin: Minimum Dilution: 20; Maximum Dilution: 30ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Researchers should empirically determine the suitability of the CD167 ddr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD167 ddr1 product has the following accession number(s) (GI #321400059) (NCBI Accession #NP_001189450.1) (Uniprot Accession #Q08345). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RABBIT ANTI HUMAN CD167 (C-TERMINAL) with the following immunoassay(s):
Testing Data #1 (Staining of formalin fixed, paraffin embedded human decidual cells with Rabbit anti Human CD167 (MBS221418))
MBS221418 detects an epitope within the C-terminal of human CD167, a Discoidin Domain Receptor (DDR) also known as DDR1. CD167, a receptor for collagen, is widely expressed in normal and transformed epithelial cells, and may regulate cell adhesion, proliferation and extracellular matrix remodelling. CD167 is a 125kD protein which is partially processed into a 62kD membrane-anchored beta-subunit and a 54kD soluble alpha-subunit. This process, also termed shedding, is significantly enhanced upon CD167 activation. CD167 has been demonstrated to be a direct transcriptional target of the p53 tumour suppressor gene, and is significantly over-expressed in breast, ovarian, oesophageal, and paediatric brain tumours.
Perservative Stabilisers: 0.1% Sodium Azide (NaN3). Immunogen: Synthetic peptide: C-terminal region of human CD167.
Histology Positive Control Tissue: Decidual cells.
Buffer Solution: Phosphate buffered saline
Antiserum Preparation: Antisera to CD167 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD167 are readily searchable from our website. Different antibodies against the same target such as CD167 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.