anti-CD180 antibody product blog
Tags: Antibody; Polyclonal Antibody; RP105; anti-CD180 antibody; CD180;
The CD180 cd180 (Catalog #MBS151419) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RP105 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s RP105 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).RP105 antibody can be used for the detection of RP105 by Western blot at 0.5 - 1 mug/mL. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa. Antibody can also be used for immunohistochemistry starting at 2 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CD180 cd180 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD180 cd180 product has the following accession number(s) (GI #1843411) (NCBI Accession #BAA12019) (Uniprot Accession #Q99467). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the RP105 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of RP105 in human spleen tissue lysate with RP105 antibody at (A) 0.5 and (B) 1 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of RP105 in human spleen tissue with RP105 antibody at 2 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of RP105 in human spleen tissue with RP105 antibody at 20 μg/mL.)
RP105 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Conjugate: Unconjugated
Immunogen: RP105 antibody was raised against a 11 amino acid synthetic peptide from near the amino terminus of human RP105.
Buffer: RP105 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD180 are readily searchable from our website. Different antibodies against the same target such as CD180 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.