anti-CD1A antibody product blog
Tags: Antibody; Polyclonal Antibody; CD1A; anti-CD1A antibody;
The CD1A cd1a (Catalog #MBS9203948) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD1A Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC).WB~~1:1000. Researchers should empirically determine the suitability of the CD1A cd1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD1A cd1a product has the following accession number(s) (GI #110618224) (NCBI Accession #NP_001754.2) (Uniprot Accession #P06126). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD1A Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (CD1A Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CD1A antibody detected the CD1A protein (arrow).)
Immunohistochemistry (IHC) (CD1A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene localizes to the plasma membrane and to recycling
vesicles of the early endocytic system. Alternatively spliced
transcript variants have been observed, but their biological
validity has not been determined.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD1A are readily searchable from our website. Different antibodies against the same target such as CD1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.