anti-CD1C antibody product blog
Tags: Antibody; Polyclonal Antibody; CD1c; anti-CD1c antibody;
The CD1C n/a (Catalog #MBS620009) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The CD1c (Cluster of differentiation antigen 1c, CD1c antigen, CD1c antigen c polypeptide, CD1c molecule, Cortical thymocyte antigen CD1c, Differentiation antigen CD1 alpha 3, R7, T cell surface glycoprotein CD1c) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD1c can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.5-1ug/ml
Western Blot: 1ug/ml. Researchers should empirically determine the suitability of the CD1C n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD1C n/a product has the following accession number(s) (GI #48146277) (Uniprot Accession #P29017). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD1c (Cluster of differentiation antigen 1c, CD1c antigen, CD1c antigen c polypeptide, CD1c molecule, Cortical thymocyte antigen CD1c, Differentiation antigen CD1 alpha 3, R7, T cell surface glycoprotein CD1c) with the following immunoassay(s):
SDS-Page (Detection of CD1c with MBS620009. Cell lysates were resolved by SDS-PAGE, transferred to an Immobilon-P membrane and immunoblotted with 1ug/ml goat anti-CD1c.)
CD1c (Cluster of differentiation antigen 1c) is a 43kD member of the CD1 family of molecules. It is expressed by thymocytes, dendritic cells and B cells, and exists as part of a noncovalent complex with 12kD B2-microglobulin. It is found in the plasma membrane and early endosomes (but not lysosomes), and is presumed to present glycolipids and acylated peptides to T cells. Mature human CD1c is a 316aa type I transmembrane glycoprotein. It contains a 285aa extracellular domain (ECD) (aa18-302) plus a 10aa cytoplasmic tail. The ECD shows one Ig-like domain (aa203-296) that associates with B2-microglobulin, and a TyrGlnAspIle internalization motif in the cytoplasmic tail. There are three potential splice variants. One shows a Trp substitution for aa327-333, a second shows an eight aa substitution for aa298-333, and a third shows a 50aa substitution for aa297-333. There appears to be no direct mouse counterpart to human CD1c.