anti-CD3 antibody product blog
Tags: Antibody; CD3; Polyclonal Antibody; anti-CD3 antibody;
The CD3 cd3e (Catalog #MBS540279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD3 epsilon Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CD3 epsilon can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Dot Blot: 1:2,000
ELISA: 1:2,000
Western Blot: 1:500-1:1,000. Researchers should empirically determine the suitability of the CD3 cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD3 cd3e product has the following accession number(s) (GI #4502671) (NCBI Accession #NP_000724.1) (Uniprot Accession #P07766). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity Purified T-cell surface glycoprotein CD3 epsilon chain precursor Antibody Mid-Region
Mediates signal transduction.
Immunogen: Mid-region epitope synthetic peptide corresponding to unique amino acid sequence on CD3 epsilon protein. Determinant: Mid-Region
Molecular Function: Receptor; GPCR signaling pathway
Structure: Heterodimer coexprassed at the cell surface with invariant subunits of CD3 labeled gamma, delta epsilon, zeta, eta.
Subcellular Location: Membrane; Single-pass type I membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD3 are readily searchable from our website. Different antibodies against the same target such as CD3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD3 also interacts with the following gene(s): CD247, CD3D, CD3G, CSK, LAT, LCK, SYK, ZAP70. Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Lymph Node, Spleen, Thymus tissues are correlated with this protein. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Carcinoma, Disease Models, Animal, Immunologic Deficiency Syndromes, Inflammation, Lung Diseases, Necrosis, Neoplasm Metastasis, Severe Combined Immunodeficiency, Vascular Diseases are some of the diseases may be linked to CD3 epsilon Antibody Affinity Purified.