anti-CDC14B antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-CDC14B antibody; CDC14B;
The CDC14B cdc14b (Catalog #MBS9213967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDC14B Antibody (Center) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. MyBioSource\'s CDC14B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS).WB~~1:1000. Researchers should empirically determine the suitability of the CDC14B cdc14b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDC14B cdc14b product has the following accession number(s) (GI #116008458) (NCBI Accession #NP_001070649.1) (Uniprot Accession #O60729). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDC14B Antibody (Center) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of CDC14B Antibody (Center) in 293 cell line lysates (35ug/lane). CDC14B (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS) (CDC14B Antibody (Center) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDC14B are readily searchable from our website. Different antibodies against the same target such as CDC14B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Kidney, Liver, Skin, Testis, Vascular tissues are correlated with this protein. CDC14B also interacts with the following gene(s): CDK1, CDK2, FZR1, PLK1.