anti-CDH5 antibody product blog
Tags: Antibody; CDH5; Polyclonal Antibody; anti-CDH5 antibody;
The CDH5 cdh5 (Catalog #MBS2517746) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDH5 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CDH5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CDH5 cdh5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDH5 cdh5 product has the following accession number(s) (GI #109730054) (NCBI Accession #AAH96364.3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDH5 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDH5 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CDH5 Polyclonal Antibody at dilution 1:50)
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Immunogen: Synthetic peptide of human CDH5. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDH5 are readily searchable from our website. Different antibodies against the same target such as CDH5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atherosclerosis, Breast Neoplasms, Cardiovascular Diseases, Colorectal Neoplasms, Heart Diseases, Hemorrhage, Inflammation, Lung Diseases, Myocardial Infarction, Necrosis are some of the diseases may be linked to CDH5 Polyclonal Antibody. The following patways have been known to be associated with this gene.