|The CDK7 cdk7 (Catalog #MBS835336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDK7 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDK7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB).
WB: 1 ug/ml. Researchers should empirically determine the suitability of the CDK7 cdk7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDK7 cdk7 product has the following accession number(s) (GI #4502743) (NCBI Accession #NP_001790) (Uniprot Accession #P50613). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDK7 antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (CDK7 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (lndicated with Arrows] in Human Kidney. Magnification is at 400X.)
Western Blot (WB) (CDK7 antibody (MBS835336) used at 0.2-1 ug/ml to detect target protein.)
Rabbit polyclonal CDK7 antibody.
Biological Significance: Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti. Immunogen: CDK7 antibody was raised in rabbit using the C terminal of CDK7 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDK7 are readily searchable from our website. Different antibodies against the same target such as CDK7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Eye, Heart, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Disease Models, Animal, Hyperplasia, Hypertrophy, Inflammation, Liver Diseases, Lung Neoplasms, Nervous System Diseases, Precancerous Conditions are some of the diseases may be linked to CDK7 antibody. The following patways have been known to be associated with this gene.