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anti-CFH antibody product blog

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Posted on 2017-03-04 01:35:26 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-CFH antibody; CFH;
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The CFH cfh (Catalog #MBS1497005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CFH Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CFH can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
Recommended dilution: WB:1:500-5000
IHC:1:20-1:200. Researchers should empirically determine the suitability of the CFH cfh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CFH cfh product has the following accession number(s) (GI #62739186) (NCBI Accession #NP_000177.2) (Uniprot Accession #P08603). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CFH Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: CFH antibody at 3ug/ml+human serumSecondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 140,52 kDa
Observed band size: 139 kDa
)
Western Blot (WB) CFH.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS1497005 at dilution 1:100)
Immunohistochemistry (IHC) CFH.

Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.

Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate: Non-conjugated. Immunogen: Recombinant human Complement factor H protein (20-270aa)
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17949 / sc-33157. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CFH are readily searchable from our website. Different antibodies against the same target such as CFH may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CFH also interacts with the following gene(s): ADM, ARMS2, CFI, HTRA1, ITGAM, PLEKHA1. The following patways have been known to be associated with this gene. Atrophy, Atypical Hemolytic Uremic Syndrome, Cardiovascular Diseases, Glomerulonephritis, Membranoproliferative, Heart Diseases, Hypertension, Inflammation, Kidney Diseases, Macular Degeneration, Macular Degeneration, Age-Related, 4 are some of the diseases may be linked to CFH Antibody. Brain, Ear, Eye, Heart, Kidney, Liver, Lung, Nerve, Skin, Vascular tissues are correlated with this protein.
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