anti-CHRNA6 antibody product blog
Tags: Antibody; Polyclonal Antibody; Chrna6; anti-CHRNA6 antibody;
The CHRNA6 chrna6 (Catalog #MBS9128243) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHRNA6 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CHRNA6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB 1:500 - 1:2000. Researchers should empirically determine the suitability of the CHRNA6 chrna6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHRNA6 chrna6 product has the following accession number(s) (GI #313482792) (NCBI Accession #NP_001186208.1) (Uniprot Accession #Q15825). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CHRNA6 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using CHRNA6 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.)
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human CHRNA6. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHRNA6 are readily searchable from our website. Different antibodies against the same target such as CHRNA6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Brain Diseases, Death, Inflammation, Kidney Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Neurotoxicity Syndromes, Poisoning, TOBACCO ADDICTION, SUSCEPTIBILITY TO are some of the diseases may be linked to CHRNA6 Polyclonal Antibody. CHRNA6 also interacts with the following gene(s): CHRNA4, CHRNA5, CHRNA7, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND.