|The CHRNA7 chrna7 (Catalog #MBS835444) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHRNA7 antibody reacts with Human, Dog, Mouse, Rat, Bovine, Chicken and may cross-react with other species as described in the data sheet. MyBioSource\'s CHRNA7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 2.5 ug/ml. Researchers should empirically determine the suitability of the CHRNA7 chrna7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHRNA7 chrna7 product has the following accession number(s) (GI #4502831) (NCBI Accession #NP_000737) (Uniprot Accession #P36544). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CHRNA7 antibody with the following immunoassay(s):
Western Blot (WB) (CHRNA7 antibody (MBS835444) used at 0.2-1 ug/ml to detect target protein.)
Rabbit polyclonal CHRNA7 antibody.
Biological Significance: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Immunogen: CHRNA7 antibody was raised in rabbit using the N terminal of CHRNA7 as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHRNA7 are readily searchable from our website. Different antibodies against the same target such as CHRNA7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone Marrow, Brain, Eye, Intestine, Kidney, Liver, Nerve, Pancreas, Thymus, Vascular tissues are correlated with this protein. Alzheimer Disease, Cognition Disorders, Inflammation, Learning Disorders, Lung Diseases, Memory Disorders, Necrosis, Neurobehavioral Manifestations, Pain, Seizures are some of the diseases may be linked to CHRNA7 antibody. CHRNA7 also interacts with the following gene(s): AKT1, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNB2, CHRNB4, JAK2, PICK1. The following patways have been known to be associated with this gene.