anti-CITED2 antibody product blog
Tags: Antibody; Polyclonal Antibody; CITED2; anti-CITED2 antibody;
The CITED2 cited2 (Catalog #MBS153523) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CITED2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CITED2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF).CITED2 antibody can be used for detection of CITED2 by Western blot at 1 - 2 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CITED2 cited2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CITED2 cited2 product has the following accession number(s) (GI #270288756) (NCBI Accession #NP_001161861) (Uniprot Accession #Q99967). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CITED2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of CITED2 in Jurkat cell lysate with CITED2 antibody at (A) 1 and (B) 2 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of CITED2 in Jurkat cells with CITED2 antibody at 20 μg/mL.)
CITED2 Antibody: CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Conjugate: Unconjugated
Immunogen: CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2.
Buffer: CITED2 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CITED2 are readily searchable from our website. Different antibodies against the same target such as CITED2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CITED2 also interacts with the following gene(s): CREBBP, ELK1, EP300, HIF1A, LHX2, TFAP2A, TFAP2B, TFAP2C.