anti-CLDN14 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-CLDN14 antibody; CLDN14;
The CLDN14 cldn14 (Catalog #MBS9128671) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLDN14 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CLDN14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB 1:500 - 1:2000. Researchers should empirically determine the suitability of the CLDN14 cldn14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CLDN14 cldn14 product has the following accession number(s) (GI #225703138) (NCBI Accession #NP_001139549.1) (Uniprot Accession #O95500). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human CLDN14. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CLDN14 are readily searchable from our website. Different antibodies against the same target such as CLDN14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Deafness, Inflammation, Kidney Calculi, Kidney Diseases, Learning Disorders are some of the diseases may be linked to CLDN14 Polyclonal Antibody. Liver tissues are correlated with this protein. CLDN14 also interacts with the following gene(s): CLDN12, CLDN9. The following patways have been known to be associated with this gene.