anti-CLEC1B antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-CLEC1B antibody; CLEC1B ;
The CLEC1B clec1b (Catalog #MBS9129243) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLEC1B Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CLEC1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the CLEC1B clec1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CLEC1B clec1b product has the following accession number(s) (GI #153252048) (NCBI Accession #NP_001092901.1) (Uniprot Accession #Q9P126). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CLEC1B Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using CLEC1B antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.)
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human CLEC1B (NP_001092901.1).
Calculated MW: 23kDa/26kDa
Observed MW: 27kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CLEC1B are readily searchable from our website. Different antibodies against the same target such as CLEC1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Liver, Lung tissues are correlated with this protein. The following patways have been known to be associated with this gene. Carcinoma, Carcinoma, Hepatocellular, Fibrosis, Hypersensitivity, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis are some of the diseases may be linked to CLEC1B Polyclonal Antibody.