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anti-CNN1 antibody product blog

Posted on 2017-08-13 11:57:03 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; Calponin; CNN1; anti-CNN1 antibody;
The CNN1 cnn1 (Catalog #MBS540744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Calponin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Calponin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB).
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500. Researchers should empirically determine the suitability of the CNN1 cnn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CNN1 cnn1 product has the following accession number(s) (GI #530414504) (NCBI Accession #XP_005259798.1) (Uniprot Accession #B7Z7E1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Calponin Antibody with the following immunoassay(s):
Immunohistochemistry (IHC)
Immunohistochemistry (IHC) CNN1.

Immunohistochemistry (IHC)
Immunohistochemistry (IHC) CNN1.

Immunohistochemistry (IHC)
Immunohistochemistry (IHC) CNN1.

Immunohistochemistry (IHC)
Immunohistochemistry (IHC) CNN1.

Affinity Purified Calponin 1, basic, smooth muscle Antibody C-epitope
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Immunogen: Synthetic peptide taken within amino acid region 200-247 on human calponin 1, basic, smooth muscle protein.
Expression: Smooth muscle, and tissues containing significant amounts of smooth muscle. Determinant: C-epitope
Molecular Function: Actin-Binding; actomyosin structure organization
Structure: Belongs to the calponin family.UniRule annotation
Contains 1 CH (calponin-homology) domain.
Contains 3 calponin-like repeats.
Subcellular Location: Cytoskeleton; Focal Adhesion. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CNN1 are readily searchable from our website. Different antibodies against the same target such as CNN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CNN1 also interacts with the following gene(s): ACTA2. The following patways have been known to be associated with this gene. Bone, Bone Marrow, Brain, Connective Tissue, Embryonic Tissue, Heart, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein. Carcinoma, Cardiovascular Diseases, Cell Transformation, Neoplastic, Disease Models, Animal, Hypertrophy, Liver Neoplasms, Lung Diseases, Neoplasm Invasiveness, Neoplasms, Experimental, Precancerous Conditions are some of the diseases may be linked to Calponin Antibody.
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