|The CoA slc27a5 (Catalog #MBS1490902) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Very long-chain acyl-CoA synthetase polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Very long-chain acyl-CoA synthetase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CoA slc27a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CoA slc27a5 product has the following accession number(s) (GI #13325057) (NCBI Accession #NP_036386.1) (Uniprot Accession #Q9Y2P5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: HRP. Immunogen: Recombinant human Very long-chain acyl-CoA synthetase protein
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-70169 / sc-70172. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CoA are readily searchable from our website. Different antibodies against the same target such as CoA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adipose Tissue, Blood, Brain, Kidney, Liver, Lung, Mammary Gland, Muscle tissues are correlated with this protein. Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fatty Liver, Fibrosis, Hepatitis, Liver Diseases are some of the diseases may be linked to Rabbit anti-human Very long-chain acyl-CoA synthetase polyclonal Antibody, HRP conjugated. CoA also interacts with the following gene(s): ACSL1, BAAT.