anti-COT2 antibody product blog
Tags: Antibody; COT2; anti-COT2 antibody; Polyclonal Antibody;
The COT2 nr2f2 (Catalog #MBS9401765) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COT2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s COT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF).Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500. Researchers should empirically determine the suitability of the COT2 nr2f2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The COT2 nr2f2 product has the following accession number(s) (GI #223555949) (NCBI Accession #NP_001138627.1) (Uniprot Accession #P24468). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the COT2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from HUVEC cells, using COT2 antibody.)
Immunofluorescence (IF) (Immunofluorescence analysis of HUVEC cells, using COT2 antibody.)
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.Ladias J.A.A., Science 251:561-565(1991).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wang L.H., Gene Expr. 1:207-216(1991).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from N-terminal of human COT2. Target Name: COT2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing COT2 are readily searchable from our website. Different antibodies against the same target such as COT2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Brain, Ear, Embryonic Tissue, Heart, Liver, Lung, Muscle, Thyroid, Vascular tissues are correlated with this protein. COT2 also interacts with the following gene(s): APOB, BCL11A, DR1, KLF4, LCK, NRP2, PAX6, PCK2, RERE, SOX9. Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Heart Diseases, Hernia, Diaphragmatic, Infertility, Male, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis are some of the diseases may be linked to COT2 Antibody.