anti-COTL1 antibody product blog
Tags: Antibody; Polyclonal Antibody; COTL1; anti-COTL1 antibody; Coactosin-like protein;
The COTL1 cotl1 (Catalog #MBS968848) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Coactosin-like protein polyclonal Antibody(COTL1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Coactosin-like protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).Recommended dilution: WB:1:500-2000
IHC:1:20-1:200. Researchers should empirically determine the suitability of the COTL1 cotl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The COTL1 cotl1 product has the following accession number(s) (GI #21624607) (NCBI Accession #NP_066972.1) (Uniprot Accession #Q14019). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-human Coactosin-like protein polyclonal Antibody(COTL1) with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: COTL1 antibody at 5ug/ml
Lane 1:mouse brain tissue
Lane 2:mouse kidney tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 16kDa
Observed band size: 16kDa
)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human breast cancer using MBS968848 at dilution 1:100)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using MBS968848 at dilution 1:100)
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate: Non-conjugated. Immunogen: Recombinant human Coactosin-like protein protein (1-142aa)
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160247. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing COTL1 are readily searchable from our website. Different antibodies against the same target such as COTL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. COTL1 also interacts with the following gene(s): ALOX5, ALOX5AP. Blood, Brain, Embryonic Tissue, Kidney, Liver, Lung, Placenta tissues are correlated with this protein. Inflammation, Lung Diseases, Lung Neoplasms are some of the diseases may be linked to Rabbit anti-human Coactosin-like protein polyclonal Antibody(COTL1).