anti-CRFR1 antibody product blog
Tags: Antibody; Polyclonal Antibody; CRFR1 / CRHR1; anti-CRFR1 antibody; CRFR1;
The CRFR1 crhr1 (Catalog #MBS242930) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CRFR1 / CRHR1 reacts with Human, RatPredicted Reactivity: Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s CRFR1 / CRHR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (13 ug/ml). Researchers should empirically determine the suitability of the CRFR1 crhr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CRFR1 crhr1 product has the following accession number(s) (GI #223717971) (NCBI Accession #NP_001138618.1) (Uniprot Accession #P34998). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human CRFR1 / CRHR1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-CRF1 antibody IHC of rat hypothalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC) (Anti-CRF1 antibody IHC of human human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing.
Usage Not Recommended: Immunocytochemistry (ICC)
Target Species: Human
Immunogen Description: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human CRF1. Percent identity with other species by BLAST analysis: Human, Monkey (100%); Marmoset (94%); Rat (82%). Immunogen Type: Synthetic peptide
Immunogen: CRFR1 / CRHR1 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human CRF1. Percent identity with other species by BLAST analysis: Human, Monkey (100%); Marmoset (94%); Rat (82%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CRFR1 are readily searchable from our website. Different antibodies against the same target such as CRFR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Anoxia, Anxiety Disorders, Brain Diseases, Cardiovascular Diseases, Depressive Disorder, Depressive Disorder, Major, Learning Disorders, Lung Diseases, Movement Disorders, Nervous System Diseases are some of the diseases may be linked to Rabbit Polyclonal to Human CRFR1 / CRHR1.