anti-CXCL12 antibody product blog
Tags: Antibody; Polyclonal Antibody; CXCL12; anti-CXCL12 antibody;
The CXCL12 cxcl12 (Catalog #MBS153708) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CXCL12 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CXCL12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC).CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunocytochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the CXCL12 cxcl12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CXCL12 cxcl12 product has the following accession number(s) (GI #296011023) (NCBI Accession #NP_001171605) (Uniprot Accession #P48061). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CXCL12 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of CXCL12 in HeLa cell lysate with CXCL12 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Immunocytochemistry (IHC) (Immunocytochemistry of CXCL12 in HeLa cells with CXCL12 antibody at 5 μg/mL.)
The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).
Conjugate: Unconjugated
Immunogen: CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12
Buffer: CXCL12 antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CXCL12 are readily searchable from our website. Different antibodies against the same target such as CXCL12 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. CXCL12 also interacts with the following gene(s): CCR4, CCR5, CXCR3, CXCR4, CXCR7, HIF1A, JAK2, SDC4, STAT3, VAV1.