anti-CYBB antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-CYBB antibody; CYBB;
The CYBB cybb (Catalog #MBS1491109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Anti Human CYBB PolyClonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s CYBB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CYBB cybb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The CYBB cybb product has the following accession number(s) (GI #3845574) (NCBI Accession #BAA34183.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Immunogen: Recombinant protein of human CYBB
Relevance: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cells respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. Storage Buffer: Store at -20 degree C or -80 degree C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYBB are readily searchable from our website. Different antibodies against the same target such as CYBB may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CYBB also interacts with the following gene(s): CYBA, MMP9, NCF1, NCF2, NCF4, RAC1, VCAM1. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Connective Tissue, Eye, Kidney, Liver, Lung, Vascular tissues are correlated with this protein. Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Granulomatous Disease, Chronic, Heart Diseases, Hypertension, Inflammation, Necrosis, Reperfusion Injury are some of the diseases may be linked to Rabbit Anti Human CYBB PolyClonal Antibody.