|The CYP17A1 cyp17a1 (Catalog #MBS1488611) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Steroid 17-alpha-hydroxylase/17, 20 lyase polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Steroid 17-alpha-hydroxylase/17,20 lyase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CYP17A1 cyp17a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CYP17A1 cyp17a1 product has the following accession number(s) (GI #4503195) (NCBI Accession #NP_000093.1) (Uniprot Accession #P05093). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: HRP. Immunogen: Recombinant human Steroid 17-alpha-hydroxylase/17,20 lyase protein
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46084 / sc-46080 / sc-46085 / sc-66850 / sc-66849. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYP17A1 are readily searchable from our website. Different antibodies against the same target such as CYP17A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CYP17A1 also interacts with the following gene(s): CYP19A1, ESR1, GATA4, HSD17B2, HSD17B3, HSD17B6, HSD3B1, HSD3B2, POMC, SRD5A1. Adrenal Gland, Bladder, Brain, Embryonic Tissue, Kidney, Mammary Gland, Muscle, Ovary, Testis, Thyroid tissues are correlated with this protein. Adrenal Hyperplasia, Congenital, Amenorrhea, Breast Neoplasms, Cardiovascular Diseases, Genital Diseases, Male, Hyperplasia, Hypertension, Hypogonadism, Ovarian Cysts, Prostatic Neoplasms are some of the diseases may be linked to Rabbit anti-human Steroid 17-alpha-hydroxylase/17, 20 lyase polyclonal Antibody, HRP conjugated. The following patways have been known to be associated with this gene.