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anti-CYP1A2 antibody product blog

Posted on 2018-05-16 14:33:20 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; CYP1A2; anti-CYP1A2 antibody;
The CYP1A2 cyp1a2 (Catalog #MBS9405122) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP1A2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CYP1A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CYP1A2 cyp1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CYP1A2 cyp1a2 product has the following accession number(s) (GI #73915100) (NCBI Accession #NP_000752.2) (Uniprot Accession #P05177). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CYP1A2 Antibody with the following immunoassay(s):
Testing Data (Gel: 6%SDS-PAGE Lysate: 40ug Human hepatocellular carcinoma tissue)
Testing Data CYP1A2.

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/40.)
Immunohistochemistry (IHC) CYP1A2.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme\'s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3\' untranslated region.

Immunogen Type: Peptide
Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human cytochrome P450, family 1, subfamily A, polypeptide 2. Target Name: CYP1A2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYP1A2 are readily searchable from our website. Different antibodies against the same target such as CYP1A2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CYP1A2 also interacts with the following gene(s): GSTM1, GSTP1, GSTT1, NR1I3, UGT1A1, UGT1A10, UGT1A6, UGT1A7, UGT1A9.
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