|The CYP21A2 cyp21a2 (Catalog #MBS9402180) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP21A2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CYP21A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the CYP21A2 cyp21a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CYP21A2 cyp21a2 product has the following accession number(s) (GI #323510663) (NCBI Accession #NP_000491.4) (Uniprot Accession #P08686). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CYP21A2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from Jurkat/293 cells, using CYP21A2 antibody.)
Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.Higashi Y., Proc. Natl. Acad. Sci. U.S.A. 83:2841-2845(1986).White P.C., Proc. Natl. Acad. Sci. U.S.A. 83:5111-5115(1986).Rodrigues N.R., EMBO J. 6:1653-1661(1987).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from C-terminal of human CYP21A2. Target Name: CYP21A2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYP21A2 are readily searchable from our website. Different antibodies against the same target such as CYP21A2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenoma, Adrenal Hyperplasia, Congenital, Brain Diseases, Congenital adrenal hyperplasia due to 21 hydroxylase deficiency, Hyperplasia, Infertility, Female, Insulin Resistance, Mental Disorders, Obesity, Pregnancy Complications are some of the diseases may be linked to CYP21A2 Antibody. The following patways have been known to be associated with this gene. Adrenal Gland, Brain, Eye, Heart, Liver, Muscle, Ovary, Spleen, Testis tissues are correlated with this protein. CYP21A2 also interacts with the following gene(s): C4A, C4B, HSD3B2, MC2R, NR5A1, POMC.