anti-CYPOR antibody product blog
Tags: Antibody; Polyclonal Antibody; CYPOR; anti-CYPOR antibody;
The CYPOR n/a (Catalog #MBS625983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYPOR, ID (NADPH-Cytochrome P450 Reductase, CPR, P450R, P450R, POR) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CYPOR can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the CYPOR n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CYPOR n/a product has the following accession number(s) (GI #343781131). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CYPOR, ID (NADPH-Cytochrome P450 Reductase, CPR, P450R, P450R, POR) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of P450R antibody (Center) in K562 cell line lysates (35ug/lane). P450R (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC) (P450R Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P450R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Immunogen: Synthetic peptide selected from the Center region of human P450R (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYPOR are readily searchable from our website. Different antibodies against the same target such as CYPOR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.