|The DAPK1 dapk1 (Catalog #MBS248654) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human DAPK1 / DAP Kinase reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s DAPK1 / DAP Kinase can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), ELISA (EIA).
ELISA (1:1000), IF (1:100 - 1:500), IHC-P (5 ug/ml). Researchers should empirically determine the suitability of the DAPK1 dapk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DAPK1 dapk1 product has the following accession number(s) (GI #89363047) (NCBI Accession #NP_004929.2) (Uniprot Accession #P53355). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal (IgG) to Human DAPK1 / DAP Kinase with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-DAPK1 / DAP Kinase antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunofluorescence (IF) (Immunofluorescence of COS7 cells, using DAPK1 Antibody. The sample on the right was incubated with synthetic peptide.)
DAPK1, a DAPK type protein kinase, is a positive mediator of gamma-interferon induced programmed cell death. It is believed to function in an early apoptotic checkpoint designed to eliminate premalignant cells from cancer development. The DAPK1 protein contains eight ankyrin repeats and two putative P-loop consensus sites. Loss of DAPK1 expression has been associated with invasive tumors.
Target Species: Human
Immunogen Description: Synthetic peptide from human DAPK1 (aa274-323). Immunogen: DAPK1 / DAP Kinase antibody was raised against synthetic peptide from human DAPK1 (aa274-323).
Antigen Modification: aa274-323. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DAPK1 are readily searchable from our website. Different antibodies against the same target such as DAPK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. DAPK1 also interacts with the following gene(s): BECN1, CDKN2A, HOXB7, MAPK1, MAPK3, PDCD6, STX1A, UNC5B. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Stomach, Vascular tissues are correlated with this protein.