|The DCTN4 dctn4 (Catalog #MBS2520433) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DCTN4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s DCTN4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the DCTN4 dctn4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DCTN4 dctn4 product has the following accession number(s) (GI #208431795) (NCBI Accession #NP_001129116.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DCTN4 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of Human breast cancer using DCTN4 Polyclonal Antibody at dilution of 1:30)
Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein. Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end. The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. In addition, Dynactin p62 is distributed in the nucleus at very high expression levels. Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
Immunogen: Recombinant protein of human DCTN4. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DCTN4 are readily searchable from our website. Different antibodies against the same target such as DCTN4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Eye, Heart, Liver, Lung tissues are correlated with this protein. The following patways have been known to be associated with this gene. Cystic Fibrosis, Pseudomonas Infections are some of the diseases may be linked to DCTN4 Polyclonal Antibody.