anti-DERL1 antibody product blog
Tags: Antibody; Polyclonal Antibody; DERL1; anti-DERL1 antibody; Der1-like domain family, member 1;
The DERL1 derl1 (Catalog #MBS618154) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Der1-like Domain Family, Member 1 (DER-1, DER1, DERL1, DERLIN-1, DERTRIN-1, FLJ13784, FLJ42092, MGC3067, PRO2577) reacts with Canine, Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Der1-like Domain Family, Member 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Western Blot and Immunohistochemistry. Researchers should empirically determine the suitability of the DERL1 derl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DERL1 derl1 product has the following accession number(s) (GI #12803283) (Uniprot Accession #Q9BUN8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell.
Immunogen: A synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251).
Cellular Localization: Subcellular localization in the endoplasmic reticulum. Positive Control: KRM (canine microsome) lysates. (BD offers commercial liver microsomes). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DERL1 are readily searchable from our website. Different antibodies against the same target such as DERL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Embryonic Tissue, Kidney, Liver, Lymph, Lymph Node, Mammary Gland, Ovary, Vascular tissues are correlated with this protein. DERL1 also interacts with the following gene(s): CFTR, US11, VCP. Breast Neoplasms, Carcinoma, Congenital Abnormalities, Fibrosis, Genetic Diseases, Inborn, Heart Defects, Congenital, Kidney Diseases, Liver Neoplasms, Neoplasms, Neurodegenerative Diseases are some of the diseases may be linked to Der1-like Domain Family, Member 1 (DER-1, DER1, DERL1, DERLIN-1, DERTRIN-1, FLJ13784, FLJ42092, MGC3067, PRO2577).