anti-DHCR24 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-DHCR24 antibody; DHCR24;
The DHCR24 dhcr24 (Catalog #MBS624611) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHCR24, ID (24-dehydrocholesterol Reductase, 3-beta-hydroxysterol delta-24-reductase, Seladin-1, Diminuto/Dwarf1 Homolog, DHCR24, KIAA0018) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s DHCR24 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the DHCR24 dhcr24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DHCR24 dhcr24 product has the following accession number(s) (GI #13375618) (NCBI Accession #NP_055577.1) (Uniprot Accession #Q15392). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the DHCR24, ID (24-dehydrocholesterol Reductase, 3-beta-hydroxysterol delta-24-reductase, Seladin-1, Diminuto/Dwarf1 Homolog, DHCR24, KIAA0018) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of anti-DHCR24 Antibody (Center) in HepG2 cell line lysates (35ug/lane). DHCR24 (arrow) was detected using the purified Pab.)
DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in DHCR24 gene have been associated with desmosterolosis. Also, reduced expression of DHCR24 gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Immunogen: Synthetic peptide selected from the Center region of human DHCR24 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DHCR24 are readily searchable from our website. Different antibodies against the same target such as DHCR24 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. DHCR24 also interacts with the following gene(s): CYP51A1, DHCR7, EBP, LSS, SC4MOL, SC5DL, SOAT1, TM7SF2, TP53. The following patways have been known to be associated with this gene. Alzheimer Disease, Atherosclerosis, Brain Diseases, Carcinoma, Hepatocellular, Desmosterolosis, Inflammation, Liver Diseases, Necrosis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to DHCR24, ID (24-dehydrocholesterol Reductase, 3-beta-hydroxysterol delta-24-reductase, Seladin-1, Diminuto/Dwarf1 Homolog, DHCR24, KIAA0018).