|The DIABLO diablo (Catalog #MBS647700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Smac, CT (DIABLO, Direct IAP Binding Protein of Low Pi, Second Mitochondrial Activator of Cell Death) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Smac can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot
Dilution: Western Blot: 1ug/ml
Optimal working dilutions to be determined by researcher. Researchers should empirically determine the suitability of the DIABLO diablo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DIABLO diablo product has the following accession number(s) (GI #9454219) (NCBI Accession #AAF87716.1) (Uniprot Accession #Q9NR28). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Inhibitors of apoptosis proteins (IAP\'s) block cell death by caspase inhibition. X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP.
Immunogen: Synthetic peptide corresponding to amino acids 222-237 of mouse Smac/DIABLO. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DIABLO are readily searchable from our website. Different antibodies against the same target such as DIABLO may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Hematologic Diseases, Leukemia, Liver Diseases, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to Smac, CT (DIABLO, Direct IAP Binding Protein of Low Pi, Second Mitochondrial Activator of Cell Death). Blood, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Prostate, Vascular tissues are correlated with this protein. DIABLO also interacts with the following gene(s): BIRC2, BIRC3, BIRC5, BIRC6, BIRC7, CASP3, CASP9, TRAF2, UBC, XIAP. The following patways have been known to be associated with this gene.